Article
Large differences in adiponectin levels have no clear effect on multiple sclerosis risk: A Mendelian randomization study.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Oct 2017
Devorak Julia, Mokry Lauren E, Morris John A, Forgetta Vincenzo, Davey Smith George, Sawcer Stephen, Richards J Brent
Abstract excerpt
BACKGROUND: Mendelian randomization (MR) studies have demonstrated strong support for an association between genetically increased body mass index and risk of multiple sclerosis (MS). The adipokine adiponectin may be a potential mechanism linking body mass to risk of MS. OBJECTIVE: To evaluate whether genetically increased adiponectin levels influence risk of MS. METHODS: Using genome-wide significant single...
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