Article
Tissue Sources for Accurate Measurement of Germline DNA Genotypes in Prostate Cancer Patients Treated With Radical Prostatectomy.
The Prostate - 1 Mar 2017
Emami Nima C, Leong Lancelote, Wan Eunice, Van Blarigan Erin L, Cooperberg Matthew R, Tenggara Imelda, Carroll Peter R, Chan June M, Witte John S, Simko Jeffry P
Abstract excerpt
BACKGROUND: Benign tissue from a tumor-containing organ is commonly the only available source for obtaining a patient's unmutated genome for use in cancer research. While it is critical to identify histologically normal tissue that is independent of the tumor lineage, few additional considerations are applied to the choice of this material for such measurements. METHODS: Normal formalin-fixed, paraffin-embedded...
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