Article
Germline Mutations and Ancestry in Prostate Cancer.
Current oncology reports - 1 Feb 2024
Bataba Eudoxie, Babcock Kevin, Isensee Kathryn A, Eldhose Binil, Kohaar Indu, Chesnut Gregory T, Dobi Albert
Abstract excerpt
PURPOSE OF REVIEW: Prostate cancer is the most frequently diagnosed non-cutaneous malignancy of men in the USA; notably, the incidence is higher among men of African, followed by European and Asian ancestry. Germline mutations and, in particular, mutations in DNA damage repair genes (DDRGs) have been implicated in the pathogenesis of prostate cancer. This review intends to discuss the implication of ancestry on...
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