Article
Gene polymorphisms of interleukin-28, p21-activated protein kinases 4, and response to interferon-α based therapy in Chinese patients with chronic hepatitis B.
Chinese medical journal - 1 Jan 2013
Yu Feng-xue, Zhang Xiao-lin, Wang Yan-ping, Ma Ning, DU Hong, Ma Jian-min, Liu Dian-wu
Abstract excerpt
BACKGROUND: Peg-Interferon-α treatment is expensive and associated with considerable adverse effects, selection of patients with the highest probability of response is essential for clinical practice. The objective of this study was to assess the relationship between the gene polymorphisms of interleukin-28 (IL-28), p21-activated protein kinase 4 (PAK4) and the response to interferon treatment in chronic...
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