PHACTR1 genotype predicts coronary artery disease in patients with familial hypercholesterolemia.

doi:10.1016/j.jacl.2018.04.012

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Article

PHACTR1 genotype predicts coronary artery disease in patients with familial hypercholesterolemia.

Journal of clinical lipidology - 1 Jan 2000

Paquette Martine, Dufour Robert, Baass Alexis

Abstract excerpt

BACKGROUND: Familial hypercholesterolemia (FH) is the most frequent autosomal codominant disease worldwide and is characterized by elevated low-density lipoprotein cholesterol and premature coronary artery disease (CAD). Polymorphisms in phosphatase and actin regulator 1 (PHACTR1) have been shown to be associated with cardiovascular risk in large genome-wide association studies studies. OBJECTIVE: The aim of the...

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Identifiers

PMID: 29784573
DOI: 10.1016/j.jacl.2018.04.012

Genes

CAD
PHACTR1

Provenance

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