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Article

Genetics of psychotropic medication induced side effects in two independent samples of bipolar patients.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2015

Fabbri Chiara, Souery Daniel, Calati Raffaella, Crisafulli Concetta, Chierchia Armando, Albani Diego, Forloni Gianluigi, Chiesa Alberto, Martines Rosalba, Sentissi Othman, Mendlewicz Julien, De Girolamo Giovanni, Serretti Alessandro

Abstract excerpt

The treatment of bipolar disorder (BD) usually requires combination therapies, with the critical issue of the emergence of adverse drug reactions (ADRs) and the possibility of low treatment adherence. Genetic polymorphisms are hypothesized to modulate the pharmacodynamics of psychotropic drugs, representing potential biological markers of ADRs. This study investigated genes involved in the regulation of...

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Brain-Derived Neurotrophic Factor
Catechol O-Methyltransferase
Drug-Related Side Effects and Adverse Reactions
Glycogen Synthase Kinase 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Glycogen Synthase Kinase 3 beta

Nuclear Receptor Subfamily 1, Group F, Member 1

Psychotropic Drugs

Receptor, Serotonin, 5-HT2A

Source

Identifiers

PMID: 25129258
DOI: 10.1007/s00702-014-1290-3

Genes

COPE
RORA
BDNF
COMT
MAPK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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