Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Establishment and characterization of a novel uterine carcinosarcoma cell line, TU-ECS-1, with mutations of TP53 and KRAS.

Human cell - 1 Apr 2017

Chiba Yohei, Sato Seiya, Itamochi Hiroaki, Suga Yasuko, Fukagawa Tomoyuki, Oumi Nao, Oishi Tetsuro, Harada Tasuku, Sugai Tamotsu, Sugiyama Toru

Abstract excerpt

A new human uterine carcinosarcoma (UCS) cell line, TU-ECS-1, was established and characterized. The morphological appearance of the cultured cells was an insular of epithelial-like cells arranged in the form of a jigsaw puzzle and mesenchymal-like cells with a spindle-shaped or fibroblast-like morphology. A relatively high proliferation rate was observed with a doubling time of 18.2 h. The chromosome number...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinosarcoma
Share to Cell Separation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to Mice, Inbred BALB C

Share to Molecular Targeted Therapy

Share to Neoplasm Transplantation

Share to Proto-Oncogene Proteins p21(ras)

Share to Uterine Neoplasms

Source

Identifiers

PMID: 27889902
DOI: 10.1007/s13577-016-0154-6

Genes

KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Establishment and characterization of a novel uterine carcinosarcoma cell line, TU-ECS-1, with mutations of TP53 and KRAS.PMID 27889902Read ↗

Uterine carcinosarcoma: Contemporary clinical summary, molecular updates, and future research opportunity.Semantic proximity Read ↗

Clinicopathological and molecular analyses of uterine carcinosarcomas using next-generation sequencing: A single-center experience.Semantic proximity Read ↗

Molecular diversity in uterine carcinosarcoma: Beyond TP53.Semantic proximity Read ↗

[Clinicopathological and gene mutation characteristics of uterine carcinosarcoma].Semantic proximity Read ↗

Characterization of a newly established uterine carcinosarcoma cell line featuring the sarcomatous phenotype of the tumor in vitro.Semantic proximity Read ↗

HDAC Inhibition Induces Cell Cycle Arrest and Mesenchymal-Epithelial Transition in a Novel Pleural-Effusion Derived Uterine Carcinosarcoma Cell Line.Semantic proximity Read ↗

Uterine carcinosarcoma is derived from a single stem cell: Anin vitro studySemantic proximity Read ↗

Expression profiles of carcinosarcoma of the uterine corpus—are these similar to carcinoma or sarcoma?Semantic proximity Read ↗

Establishment and characterization of a new cell line (SKS) from neuroendocrine small cell carcinoma of the uterine cervix and its chemosensitivity.Semantic proximity Read ↗

miR-200c-driven Mesenchymal-To-Epithelial Transition is a Therapeutic Target in Uterine Carcinosarcomas.Semantic proximity Read ↗

Cooperation of Sox4 with β-catenin/p300 complex in transcriptional regulation of the Slug gene during divergent sarcomatous differentiation in uterine carcinosarcomaSemantic proximity Read ↗

Establishment of a HPV and p53-mutation-negative human cell line (CA) derived from a squamous carcinoma of the uterine cervix.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.