Establishment of a HPV and p53-mutation-negative human cell line (CA) derived from a squamous carcinoma of the uterine cervix.

doi:10.1016/j.ygyno.2003.09.014

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Article

Establishment of a HPV and p53-mutation-negative human cell line (CA) derived from a squamous carcinoma of the uterine cervix.

Gynecologic oncology - 1 Jan 2004

Isaka Keiichi, Nishi Hirotaka, Osakabe Yumi, Miyata Machiko, Hokamura Mitsuyasu, Nakada Toshihide, Itokazu Osamu, Takayama Masaomi

Abstract excerpt

OBJECTIVE: Well-characterized human cancer cell lines are important research resources for studying cancer cell biology, as well as for developing new strategies against cancer cell growth and progression. We present a new cell line, CA, established from an invasive non-keratinizing squamous cell carcinoma of the uterine cervix in 36-year-old patient. METHODS: We measured the doubling time of CA cells. To...

Topics

Adult
Aneuploidy
Animals
Biomarkers, Tumor
Carcinoma, Squamous Cell
Cell Line, Tumor
Cyclin-Dependent Kinase Inhibitor p16
Female
Genes, p53
Humans
Immunohistochemistry
Mice
Mice, Nude

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neoplasm Transplantation

Papillomaviridae

Polymerase Chain Reaction

Transplantation, Heterologous

Source

Open in PubMed

Identifiers

PMID: 14751132
DOI: 10.1016/j.ygyno.2003.09.014

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