Article
Asthma endophenotypes and polymorphisms in the histamine receptor HRH4 gene.
International archives of allergy and immunology - 1 Jan 2012
Simon Tünde, Semsei Agnes F, Ungvári Ildikó, Hadadi Eva, Virág Viktor, Nagy Adrienne, Vangor Mónika S, László Valéria, Szalai Csaba, Falus András
Abstract excerpt
BACKGROUND: Histamine as an inflammatory mediator plays an important role in chronic allergic and asthmatic conditions. However, the role of genetic polymorphisms of the histamine receptor HRH4 (histamine receptor H4) gene in asthma susceptibility and endophenotypes has not been studied yet. Our aim was to investigate the possible association between single nucleotide polymorphisms (SNPs) in the HRH4 gene and...
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