Article
Helicobacter pylori outer membrane protein, HomC, shows geographic dependent polymorphism that is influenced by the Bab family.
Journal of microbiology (Seoul, Korea) - 1 Dec 2016
Kim Aeryun, Servetas Stephanie L, Kang Jieun, Kim Jinmoon, Jang Sungil, Choi Yun Hui, Su Hanfu, Jeon Yeong-Eui, Hong Youngmin A, Yoo Yun-Jung, Merrell D Scott, Cha Jeong-Heon
Abstract excerpt
The array of outer membrane proteins (OMPs) found in Helicobacter pylori provides a crucial component for persistent colonization within the gastric niche. Not only does H. pylori harbor a wide number of OMPs, but these OMPs often vary across strains; this likely contributes to immune evasion, adaptation during long term colonization, and potentially differential disease progression. Previous work from our group...
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