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Helicobacter pylori bab Paralog Distribution and Association with cagA, vacA, and homA/B Genotypes in American and South Korean Clinical Isolates.

PloS one - 1 Jan 2015

Kim Aeryun, Servetas Stephanie L, Kang Jieun, Kim Jinmoon, Jang Sungil, Cha Ho Jin, Lee Wan Jin, Kim June, Romero-Gallo Judith, Peek Richard M, Merrell D Scott, Cha Jeong-Heon

Abstract excerpt

Helicobacter pylori genetic variation is a crucial component of colonization and persistence within the inhospitable niche of the gastric mucosa. As such, numerous H. pylori genes have been shown to vary in terms of presence and genomic location within this pathogen. Among the variable factors, the Bab family of outer membrane proteins (OMPs) has been shown to differ within subsets of strains. To better...

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PMID: 26317221
DOI: 10.1371/journal.pone.0137078
PMCID: PMC4552749

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