Article
Evaluation of the clinical significance of homB, a novel candidate marker of Helicobacter pylori strains associated with peptic ulcer disease.
The Journal of infectious diseases - 1 Nov 2008
Oleastro Mónica, Cordeiro Rita, Ferrand Jonathan, Nunes Baltazar, Lehours Philippe, Carvalho-Oliveira Isabel, Mendes Ana I, Penque Deborah, Monteiro Lurdes, Mégraud Francis, Ménard Armelle
Abstract excerpt
BACKGROUND: homB codes for a putative Helicobacter pylori outer membrane protein and has previously been associated with peptic ulcer disease (PUD) in children. METHODS: A total of 190 H. pylori strains isolated from children and adults were studied to evaluate the clinical importance of the homB gene. In vitro experiments were performed to identify HomB mechanisms of bacterial pathogenicity. RESULTS:...
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