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Article

Evidence of bottleneck effect on hepatitis C virus transmission between a couple under interferon based therapy.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jan 2017

da Silva Rafael Alves, de Carvalho Isabel Maria Vicente Guedes, de Matos Renata Prandini Adum, Yamasaki Lilian Hiromi Tomonari, Bittar Cíntia, Rahal Paula, Jardim Ana Carolina Gomes

Abstract excerpt

Issues on the correlation of viral genetic diversity and treatment response to the hepatitis C infection remain uncertain. The bottleneck effect dictates the characteristics of the viral population that will establish the infection in a new host and is related to how the immune system and treatment will be effective against the virus. Here we evaluated the phylogenetic characteristics of quasispecies population...

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Identifiers

PMID: 27888038
DOI: 10.1016/j.meegid.2016.11.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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