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DNA Methylation at Diagnosis is Associated with Response to Disease-Modifying Drugs in Early Rheumatoid Arthritis

25 Nov 2016

Abstract excerpt

AIM: A proof-of-concept study to explore whether DNA methylation at first diagnosis is associated with response to disease-modifying antirheumatic drugs (DMARDs) in patients with early rheumatoid arthritis (RA). PATIENTS & METHODS: DNA methylation was quantified in T-lymphocytes from 46 treatment-naive patients using HumanMethylation450 BeadChips. Treatment response was determined in 6 months using the European...

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PMID: 27885849
DOI: 10.2217/epi-2016-0042

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