Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis

3 May 2018

Abstract excerpt

DNA methylation is an important epigenetic modification that is known to be altered in rheumatoid arthritis synovial fibroblasts (RASF). Here, we compared the status of promoter DNA methylation of SF from patients with very early RA with SF from patients with resolving arthritis, fully established RA and from non-arthritic patients. DNA was hybridized to Infinium Human methylation 450k and 850k arrays and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Share to Lymphoma Diagnosis and Treatment
Share to Musculoskeletal synovial abnormalities and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29743579
DOI: 10.1038/s41598-018-24240-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosisPMID 29743579Read ↗

Genome-Wide Profiling in Treatment-Naive Early Rheumatoid Arthritis Reveals DNA Methylome Changes in T and B LymphocytesSemantic proximity Read ↗

Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processesSemantic proximity Read ↗

Differential CpG DNA methylation in peripheral naïve CD4+ T-cells in early rheumatoid arthritis patientsSemantic proximity Read ↗

DNA Methylation as a Future Therapeutic and Diagnostic Target in Rheumatoid ArthritisSemantic proximity Read ↗

An imprinted rheumatoid arthritis methylome signature reflects pathogenic phenotypeSemantic proximity Read ↗

Next-Generation Sequencing Profiles of the Methylome and Transcriptome in Peripheral Blood Mononuclear Cells of Rheumatoid ArthritisSemantic proximity Read ↗

DNA Methylome Signature in Synoviocytes From Patients With Early Rheumatoid Arthritis Compared to Synoviocytes From Patients With Longstanding Rheumatoid ArthritisSemantic proximity Read ↗

Epigenetics in the pathogenesis of RA.Semantic proximity Read ↗

Epigenetic contributions in the development of rheumatoid arthritisSemantic proximity Read ↗

Computationally expanding infinium HumanMethylation450 BeadChip array data to reveal distinct DNA methylation patterns of rheumatoid arthritisSemantic proximity Read ↗

Differential DNA methylation patterns in whole blood from ACPA-positive patients with DMARD-naïve rheumatoid arthritis at clinical disease onsetSemantic proximity Read ↗

Assessing the potential of epigenetic targets as biomarkers in the diagnosis and treatment of rheumatoid arthritisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.