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Article

Differential Methylation as a Biomarker of Response to Etanercept in Patients With Rheumatoid Arthritis

27 Jan 2016

Abstract excerpt

OBJECTIVE: Biologic drug therapies represent a huge advance in the treatment of rheumatoid arthritis (RA). However, very good disease control is achieved in only 30% of patients, making identification of biomarkers of response a research priority. We undertook this study to test our hypothesis that differential DNA methylation patterns may provide biomarkers predictive of response to tumor necrosis factor...

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PMID: 26814849
DOI: 10.1002/art.39590

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