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Article

Characterization and management of long runs of homozygosity in parental nucleus lines and their associated crossbred progeny.

Genetics, selection, evolution : GSE - 24 Nov 2016

Howard Jeremy T, Tiezzi Francesco, Huang Yijian, Gray Kent A, Maltecca Christian

Abstract excerpt

BACKGROUND: In nucleus populations, regions of the genome that have a high frequency of runs of homozygosity (ROH) occur and are associated with a reduction in genetic diversity, as well as adverse effects on fitness. It is currently unclear whether, and to what extent, ROH stretches persist in the crossbred genome and how genomic management in the nucleus population might impact low diversity regions and its...

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Identifiers

PMID: 27884108
DOI: 10.1186/s12711-016-0269-y
PMCID: PMC5123398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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