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Runs of homozygosity and analysis of inbreeding depression.

Journal of animal science - 1 Dec 2020

Sumreddee Pattarapol, Toghiani Sajjad, Hay El Hamidi, Roberts Andrew, Aggrey Samuel E, Rekaya Romdhane

Abstract excerpt

Pedigree information was traditionally used to assess inbreeding. The availability of high-density marker panels provides an alternative to assess inbreeding, particularly in the presence of incomplete and error-prone pedigrees. Assessment of autozygosity across chromosomal segments using runs of homozygosity (ROH) has emerged as a valuable tool to estimate inbreeding due to its general flexibility and ability to...

Topics

Animals
Cattle
Genotype
Homozygote
Inbreeding
Inbreeding Depression
Pedigree
Polymorphism, Single Nucleotide

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33180906
DOI: 10.1093/jas/skaa361
PMCID: PMC7846130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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