Measles virus from a long-term persistently infected human T lymphoblastoid cell line, in contrast to the cytocidal parental virus, establishes an immediate persistence in the original cell line.

Abstract excerpt

To investigate the mechanisms of measles virus (MV) establishment and maintenance of persistence in lymphoid cells, we have established a long-term persistent infection with MV, Edmonston strain, in the human T lymphoblastoid cell line MOLT4, which has been in continuous culture for over 8 years....

Topics

• Antibodies, Viral
• Antigens, Viral
• Cell Death
• Cell Fusion
• Defective Viruses
• Genome, Viral
• Humans
• Leukemia, Lymphoid
• Measles virus
• Phenotype
• Superinfection
• T-Lymphocytes