Article
Ephrin-B reverse signaling is required for formation of strictly contralateral auditory brainstem pathways.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 21 Jul 2010
Hsieh Candace Y, Nakamura Paul A, Luk Samantha O, Miko Ilona J, Henkemeyer Mark, Cramer Karina S
Abstract excerpt
Specificity in the projections from the mammalian ventral cochlear nucleus (VCN) is essential for sound localization. Globular bushy cells project from the VCN to the medial nucleus of the trapezoid body (MNTB) on the contralateral, but not the ipsilateral, side of the brainstem, terminating in large synaptic endings known as calyces of Held. The precision in this pathway is critical for the computation of...
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