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Article

Deep phenotyping unveils hidden traits and genetic relations in subtle mutants.

Nature communications - 23 Nov 2016

San-Miguel Adriana, Kurshan Peri T, Crane Matthew M, Zhao Yuehui, McGrath Patrick T, Shen Kang, Lu Hang

Abstract excerpt

Discovering mechanistic insights from phenotypic information is critical for the understanding of biological processes. For model organisms, unlike in cell culture, this is currently bottlenecked by the non-quantitative nature and perceptive biases of human observations, and the limited number of reporters that can be simultaneously incorporated in live animals. An additional challenge is that isogenic...

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Identifiers

PMID: 27876787
DOI: 10.1038/ncomms12990
PMCID: PMC5122966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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