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Article

Wild worm embryogenesis harbors ubiquitous polygenic modifier variation.

eLife - 22 Aug 2015

Paaby Annalise B, White Amelia G, Riccardi David D, Gunsalus Kristin C, Piano Fabio, Rockman Matthew V

Abstract excerpt

Embryogenesis is an essential and stereotypic process that nevertheless evolves among species. Its essentiality may favor the accumulation of cryptic genetic variation (CGV) that has no effect in the wild-type but that enhances or suppresses the effects of rare disruptions to gene function. Here, we adapted a classical modifier screen to interrogate the alleles segregating in natural populations of Caenorhabditis...

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Identifiers

PMID: 26297805
DOI: 10.7554/eLife.09178
PMCID: PMC4569889

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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