Article
Autonomous screening of C. elegans identifies genes implicated in synaptogenesis.
Nature methods - 1 Oct 2012
Crane Matthew M, Stirman Jeffrey N, Ou Chan-Yen, Kurshan Peri T, Rehg James M, Shen Kang, Lu Hang
Abstract excerpt
Morphometric studies in multicellular organisms are generally performed manually because of the complexity of multidimensional features and lack of appropriate tools for handling these organisms. Here we present an integrated system that identifies and sorts Caenorhabditis elegans mutants with altered subcellular traits in real time without human intervention. We performed self-directed screens 100 times faster...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.