Article
Biological fitness and natural selection of amantadine resistant variants of avian influenza H5N1 viruses.
Virus research - 15 Jan 2017
Abdelwhab E M, Veits Jutta, Mettenleiter Thomas C
Abstract excerpt
Outbreaks caused by the highly pathogenic H5N1 avian influenza virus (A/H5N1) devastated the poultry industry in several countries and posed a significant pandemic threat. In addition to culling of infected poultry and vaccination, amantadine has been applied in poultry in some countries to control the spread of the virus. The prevalence of the amantadine resistance marker at position 31 (Ser31Asn) of the M2...
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