Article
Diversifying evolution of highly pathogenic H5N1 avian influenza virus in Egypt from 2006 to 2011.
Virus genes - 1 Aug 2012
Abdelwhab E M, Arafa Abdel-Satar, Stech Jürgen, Grund Christian, Stech Olga, Graeber-Gerberding Marcus, Beer Martin, Hassan Mohamed K, Aly Mona M, Harder Timm C, Hafez Hafez M
Abstract excerpt
An evolutionary analysis was conducted of 354 hemagglutinin (HA) and 208 neuraminidase (NA) genes, including newly generated sequences of 5 HA and 30 NA, of Egyptian H5N1 clade 2.2.1 viruses isolated from poultry and humans. Five distinct phylogenetically distinguishable clusters arose from a monophyletic origin since 2006. Only two clusters remained in circulation after 2009: (i) A cluster of viruses arose in...
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