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Article

Detecting amyloid-β plaques in Alzheimer's disease.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Baltes Christof, Princz-Kranz Felicitas, Rudin Markus, Mueggler Thomas

Abstract excerpt

One of the major neuropathological changes characteristic of Alzheimer's disease (AD) is deposits of beta-amyloid plaques and neurofibrillary tangles in neocortical and subcortical regions of the AD brain. The histochemical detection of these lesions in postmortem brain tissue is necessary for definitive diagnosis of AD. Methods for their in vivo detection would greatly aid the diagnosis of AD in early stages...

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PMID: 21279620
DOI: 10.1007/978-1-61737-992-5_26

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