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Article

Impact of clinical factors on outcome of leukemia patients with TLS-ERG fusion gene.

Leukemia & lymphoma - 1 Jul 2017

Pan Jing, Zhang Yang, Zhao Yan-Li, Yang Jun-Fang, Zhang Jian-Ping, Liu Hong-Xing, Wu Tong, Tong Chun-Rong

Abstract excerpt

We report the clinical features and outcome of 22 TLS-ERG+leukemia patients (20 AML and 2 B-ALL). TLS-ERG was tightly associated with extramedullary disease (EMD), complex chromosome abnormalities, and high risk gene mutations including IKZF1, WT1, TET2, NOTCH2, and PHF6. The 6-month leukemia free survival (LFS) with and without EMD was 75% and 83.3% (p = .017). 11/20 AML patients received allogeneic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27874290
DOI: 10.1080/10428194.2016.1260124

Genes

ERG
EMD
IKZF1
NOTCH2
PHF6
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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