Article
The role of rs1984112_G at CD36 gene in increasing reticulocyte level among sickle cell disease patients.
Hematology (Amsterdam, Netherlands) - 1 Apr 2017
Kalai Miniar, Dridi Marwa, Chaouch Leila, Moumni Imen, Ouragini Houyem, Darragi Imen, Boudrigua Imen, Chaouachi Dorra, Mellouli Fethi, Bejaoui Mohamed, Abbes Salem
Abstract excerpt
AIMS AND BACKGROUND: Mediators of adhesion become a potential new target for pharmacological therapy to struggle the complications of sickle cell disease (SCD). Several mechanisms for increased adherence have been postulated and the well-studied are CD36 and VLA4 which encoded by ITGA4. Herein, we sought to determine whether one polymorphism of CD36 namely: rs1984112 and three exons of ITGA4 (4, 5, and 6) are...
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