ABCC3 Polymorphisms and mRNA Expression Influence the Concentration of a Carboxylic Acid Metabolite in Patients on Clopidogrel and Aspirin Therapy.

doi:10.1111/bcpt.12703

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Article

ABCC3 Polymorphisms and mRNA Expression Influence the Concentration of a Carboxylic Acid Metabolite in Patients on Clopidogrel and Aspirin Therapy.

Basic & clinical pharmacology & toxicology - 1 May 2017

Luchessi André Ducati, Concheiro Marta, Germano Juliana de Freitas, Silbiger Vivian Nogueira, Bortolin Raul Hernandes, Cruz Angelines, Quintela Oscar, Brion Maria, Carracedo Angel, Iñiguez Andres, Bravo Marisol, López-Rivadulla Manuel, Hirata Rosario Dominguez Crespo, Sousa Amanda Guerra Moraes Rego, Hirata Mario Hiroyuki

Abstract excerpt

Acetylsalicylic acid (ASA) and clopidogrel combined therapy has been reported to be beneficial in patients with acute coronary syndrome (ACS). Antiplatelet drug resistance, especially to clopidogrel, is a multifactorial phenomenon that affects a large number of ACS patients. The genetic contribution to this drug response is not fully elucidated. We investigated the relationship of ABC-type efflux subfamily C...

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Identifiers

PMID: 27862978
DOI: 10.1111/bcpt.12703

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ABCC3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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