Article
Single nucleotide polymorphism of CYP3A5*3 contributes to clopidogrel resistance in coronary artery disease patients among Tamilian population.
Molecular biology reports - 1 Nov 2014
Priyadharsini Rajendran, Shewade Deepak Gopal, Subraja Kumaresan, Ravindra Byrappa Kempalalakshmamma, Umamaheswaran Gurusamy, Dkhar Steven Aibor, Satheesh Santhosh, Sridhar Magadi Gopalakrishna, Narayan Sunil K, Adithan Chandrasekaran
Abstract excerpt
Clopidogrel is an antiplatelet drug. It is used for the treatment as well as for the prophylaxis of coronary artery disease. Clopidogrel resistance is an emerging problem in clinical settings. The aim of the present study was to evaluate the effect of CYP3A5*3 genetic polymorphism on clopidogrel resistance. One hundred and forty-seven patients from outpatient Department of Cardiology on 75 mg/day of clopidogrel...
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