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Article

Combined influence of ABCB1 genetic polymorphism and DNA methylation on aspirin resistance in Chinese ischemic stroke patients.

Acta neurologica Belgica - 1 Aug 2022

Xu Liyan, Wang Yan

Abstract excerpt

Genetic variants of ABCB1 may affect intestinal absorption of aspirin (ASA). However, it is unclear whether ABCB1 polymorphisms and DNA methylation are associated with ASA efficacy for ischemic stroke. Our aims is to investigate the association between ABCB1 polymorphisms and methylation status on the antiplatelet effects of ASA in Chinese Han ischemic stroke patients. This is a prospective cohort analysis of...

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PMID: 34089489
DOI: 10.1007/s13760-021-01714-1

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