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Article

Association of Transforming Growth Factor β1 Gene Polymorphisms and Inflammatory Factor Levels with Susceptibility to Sepsis.

Genetic testing and molecular biomarkers - 1 Mar 2021

Zheng Ruibing, Fu Zhongmin, Zhao Zimiao

Abstract excerpt

Objective: To study the association of transforming growth factor β1 (TGF-β1) gene single nucleotide polymorphisms (SNPs) and plasma TGF-β1 levels with susceptibility to sepsis. Methods: The genotypes of the TGF-β1 gene rs1800469, rs1800468, rs1800470, and rs1800471 loci in 285 sepsis patients (119 patients with severe sepsis and 166 patients with mild sepsis) and 285 healthy individuals (control group) were...

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PMID: 33734893
DOI: 10.1089/gtmb.2020.0143

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