Genetic variant rs16944 in IL1B gene is a risk factor for early-onset sepsis susceptibility and outcome in preterm infants.

doi:10.1007/s00011-019-01301-4

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Article

Genetic variant rs16944 in IL1B gene is a risk factor for early-onset sepsis susceptibility and outcome in preterm infants.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Feb 2020

Varljen Tatjana, Sekulovic Gordana, Rakic Olgica, Maksimovic Nela, Jekic Biljana, Novakovic Ivana, Damnjanovic Tatjana

Abstract excerpt

OBJECTIVE: Interleukin-1-B (IL1B) is a proinflammatory cytokine that plays an important role in sepsis. The aim of this study was to evaluate the relationships between IL1B-511G/A polymorphism and susceptibility and outcome of early-onset sepsis (EOS) in preterm infants. METHODS: DNA was extracted from the buccal swabs of 471 (285 with EOS and 186 control) preterm infants. Genotypes of rs16944 polymorphism were...

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PMID: 31863173
DOI: 10.1007/s00011-019-01301-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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