Article
The IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock.
Journal of innate immunity - 1 Jan 2018
Nakada Taka-Aki, Wacharasint Petch, Russell James A, Boyd John H, Nakada Emiri, Thair Simone A, Shimada Tadanaga, Walley Keith R
Abstract excerpt
BACKGROUND: The IL10 family of genes includes crucial immune regulators. We tested the hypothesis that single nucleotide polymorphisms (SNPs) in IL10, IL19, IL20, and IL24 of the IL10 family gene cluster alter the clinical outcome of septic shock. METHODS: Patients with septic shock (n = 1,193) were genotyped for 13 tag SNPs of IL10, IL19, IL20, and IL24. IL20 gene expression was measured in genotyped...
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