Association between breast cancer genetic susceptibility variants and terminal duct lobular unit involution of the breast.

doi:10.1002/ijc.30512

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Article

Association between breast cancer genetic susceptibility variants and terminal duct lobular unit involution of the breast.

International journal of cancer - 15 Feb 2017

Bodelon Clara, Oh Hannah, Chatterjee Nilanjan, Garcia-Closas Montserrat, Palakal Maya, Sherman Mark E, Pfeiffer Ruth M, Geller Berta, Vacek Pamela, Weaver Donald L, Chicoine Rachael, Papathomas Daphne, Xiang Jackie, Patel Deesha A, Khodr Zeina G, Linville Laura, Clare Susan E, Visscher Daniel W, Mies Carolyn, Hewitt Stephen M, Brinton Louise A, Storniolo Anna Maria V, He Chunyan, Chanock Stephen J, Gierach Gretchen L, Figueroa Jonine D

Abstract excerpt

Terminal duct lobular units (TDLUs) are the predominant source of future breast cancers, and lack of TDLU involution (higher TDLU counts, higher acini count per TDLU and the product of the two) is a breast cancer risk factor. Numerous breast cancer susceptibility single nucleotide polymorphisms (SNPs) have been identified, but whether they are associated with TDLU involution is unknown. In a pooled analysis of...

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PMID: 27859137
DOI: 10.1002/ijc.30512
PMCID: PMC5167645

Genes

FOXQ1
PEX14
RANBP9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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