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Article

A genome-wide association study of mammographic texture variation.

Breast cancer research : BCR - 7 Nov 2022

Liu Yuxi, Chen Hongjie, Heine John, Lindstrom Sara, Turman Constance, Warner Erica T, Winham Stacey J, Vachon Celine M, Tamimi Rulla M, Kraft Peter, Jiang Xia

Abstract excerpt

BACKGROUND: Breast parenchymal texture features, including grayscale variation (V), capture the patterns of texture variation on a mammogram and are associated with breast cancer risk, independent of mammographic density (MD). However, our knowledge on the genetic basis of these texture features is limited. METHODS: We conducted a genome-wide association study of V in 7040 European-ancestry women. V assessments...

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Identifiers

PMID: 36344993
DOI: 10.1186/s13058-022-01570-8
PMCID: PMC9639267

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