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Article

Evidence of an epistatic effect between Dysbindin-1 and Neuritin-1 genes on the risk for schizophrenia spectrum disorders.

European psychiatry : the journal of the Association of European Psychiatrists - 1 Feb 2017

Prats C, Arias B, Moya-Higueras J, Pomarol-Clotet E, Parellada M, González-Pinto A, Peralta V, Ibáñez M I, Martín M, Fañanás L, Fatjó-Vilas M

Abstract excerpt

BACKGROUND: The interest in studying gene-gene interactions is increasing for psychiatric diseases such as schizophrenia-spectrum disorders (SSD), where multiple genes are involved. Dysbindin-1 (DTNBP1) and Neuritin-1 (NRN1) genes have been previously associated with SSD and both are involved in synaptic plasticity. We aimed to study whether these genes show an epistatic effect on the risk for SSD. METHODS: The...

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Source

Identifiers

PMID: 27855309
DOI: 10.1016/j.eurpsy.2016.07.006

Genes

DTNBP1
NRN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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