Article
Association of schizophrenia with DTNBP1 but not with DAO, DAOA, NRG1 and RGS4 nor their genetic interaction.
Journal of psychiatric research - 1 Mar 2008
Vilella Elisabet, Costas Javier, Sanjuan Julio, Guitart Míriam, De Diego Yolanda, Carracedo Angel, Martorell Lourdes, Valero Joaquín, Labad Antonio, De Frutos Rosa, Nájera Carmen, Moltó M Dolores, Toirac Ivette, Guillamat Roser, Brunet Anna, Vallès Vicenç, Pérez Lucía, Leon Melquíades, de Fonseca Fernando Rodríguez, Phillips Christopher, Torres María
Abstract excerpt
Recent reports indicate that DAO, DAOA, DTNBP1, NRG1 and RGS4 are some of the most-replicated genes implicated in susceptibility to schizophrenia. Also, the functions of these genes could converge in a common pathway of glutamate metabolism. The aim of this study was to evaluate if each of these genes, or their interaction, was associated with schizophrenia. A case-control study was conducted in 589 Spanish...
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