Involvement of NRN1 gene in schizophrenia-spectrum and bipolar disorders and its impact on age at onset and cognitive functioning.

doi:10.3109/15622975.2015.1093658

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Article

Involvement of NRN1 gene in schizophrenia-spectrum and bipolar disorders and its impact on age at onset and cognitive functioning.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Jan 2016

Fatjó-Vilas Mar, Prats Claudia, Pomarol-Clotet Edith, Lázaro Luisa, Moreno Carmen, González-Ortega Itxaso, Lera-Miguel Sara, Miret Salvador, Muñoz Ma José, Ibáñez Ignacio, Campanera Sílvia, Giralt-López Maria, Cuesta Manuel J, Peralta Victor, Ortet Generós, Parellada Mara, González-Pinto Ana, McKenna Peter J, Fañanás Lourdes

Abstract excerpt

OBJECTIVES: Neuritin 1 gene (NRN1) is involved in neurodevelopment processes and synaptic plasticity and its expression is regulated by brain-derived neurotrophic factor (BDNF). We aimed to investigate the association of NRN1 with schizophrenia-spectrum disorders (SSD) and bipolar disorders (BPD), to explore its role in age at onset and cognitive functioning, and to test the epistasis between NRN1 and BDNF....

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Identifiers

PMID: 26700405
DOI: 10.3109/15622975.2015.1093658

Genes

NRN1
BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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