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Article

Molecular analysis of the factorless internal ribosome entry site in Cricket Paralysis virus infection.

Scientific reports - 17 Nov 2016

Kerr Craig H, Ma Zi Wang, Jang Christopher J, Thompson Sunnie R, Jan Eric

Abstract excerpt

The dicistrovirus Cricket Paralysis virus contains a unique dicistronic RNA genome arrangement, encoding two main open reading frames that are driven by distinct internal ribosome entry sites (IRES). The intergenic region (IGR) IRES adopts an unusual structure that directly recruits the ribosome and drives translation of viral structural proteins in a factor-independent manner. While structural, biochemical, and...

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PMID: 27853311
DOI: 10.1038/srep37319
PMCID: PMC5112510

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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