Article
The 712A/G polymorphism of Brain-derived neurotrophic factor is associated with Parkinson's disease but not Major Depressive Disorder in a Chinese Han population.
Biochemical and biophysical research communications - 6 May 2011
Chen Ling, Wang Yang, Xiao Hong, Wang Li, Wang Chun, Guo Suwan, Zhao Yanyan, Hua Ping, Liu Weiguo, Zhang Ning
Abstract excerpt
BACKGROUND: Overlaps in clinical, pathological and molecular characteristics of Parkinson's disease (PD) and Major Depressive Disorder (MD-D) have promoted association studies in search of common genetic risk factors that may predispose or modify this spectrum of disorders. Experimental and clinical data suggest that genetic variations in Brain-derived neurotrophic factor (BDNF) gene may increase the risk for PD...
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