Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of the Relationship Between Enzymatic and Antiviral Activities of the Chicken Oligoadenylate Synthetase-Like.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Feb 2017

Tag-El-Din-Hassan Hassan T, Sasaki Nobuya, Torigoe Daisuke, Morimatsu Masami, Agui Takashi

Abstract excerpt

The oligoadenylate synthetase (OAS) is well known as an antiviral factor against the flavivirus infection in mammals. It is known that the oligoadenylate synthetase-like (ChOAS-L) gene is only present in the chicken genome. It has been shown in the previous report that the ChOAS-L possesses enzymatic activity to convert ATP into 2'-5'-linked oligoadenylates and antiviral activity against West Nile virus (WNV)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 2',5'-Oligoadenylate Synthetase
Share to Antiviral Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chickens

Share to Enzyme Activation

Share to Host-Pathogen Interactions

Share to Protein Stability

Share to Virus Replication

Share to West Nile virus

Source

Identifiers

PMID: 27849431
DOI: 10.1089/jir.2016.0012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of the Relationship Between Enzymatic and Antiviral Activities of the Chicken Oligoadenylate Synthetase-Like.PMID 27849431Read ↗

Function of ubiquitin-like domain of chicken 2'-5'-oligoadenylate synthetase in conformational stability.Semantic proximity Read ↗

The chicken 2'-5' oligoadenylate synthetase A inhibits the replication of West Nile VirusSemantic proximity Read ↗

Oligoadenylate synthase-like (OASL) proteins: dual functions and associations with diseases.Semantic proximity Read ↗

Conserved Active-Site Residues Associated with OAS Enzyme Activity and Ubiquitin-Like Domains Are Not Required for the Antiviral Activity of goOASL Protein against Avian Tembusu Virus.Semantic proximity Read ↗

The large form of human 2′,5′-Oligoadenylate Synthetase (OAS3) exerts antiviral effect against Chikungunya virusSemantic proximity Read ↗

Identification of 2′-5′-Oligoadenylate Synthetase-Like Gene in Goose: Gene Structure, Expression Patterns, and Antiviral Activity Against Newcastle Disease VirusSemantic proximity Read ↗

Distinct Antiviral Roles for Human 2′,5′-Oligoadenylate Synthetase Family Members against Dengue Virus InfectionSemantic proximity Read ↗

2',5'-oligoadenylate synthetase gene in chicken: gene structure, distribution of alleles and their expression.Semantic proximity Read ↗

2'-5' oligoadenylate synthetase shares active site architecture with the archaeal CCA-adding enzyme.Semantic proximity Read ↗

Viral determinants in the NS3 helicase and 2K peptide that promote West Nile virus resistance to antiviral action of 2′,5′-oligoadenylate synthetase 1bSemantic proximity Read ↗

Porcine 2′, 5′‐oligoadenylate synthetases inhibit Japanese encephalitis virus replication in vitroSemantic proximity Read ↗

Two types of chicken 2',5'-oligoadenylate synthetase mRNA derived from alleles at a single locus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.