Article
An artificial metalloenzyme with the kinetics of native enzymes.
Science (New York, N.Y.) - 7 Oct 2016
Dydio P, Key H M, Nazarenko A, Rha J Y-E, Seyedkazemi V, Clark D S, Hartwig J F
Abstract excerpt
Natural enzymes contain highly evolved active sites that lead to fast rates and high selectivities. Although artificial metalloenzymes have been developed that catalyze abiological transformations with high stereoselectivity, the activities of these artificial enzymes are much lower than those of natural enzymes. Here, we report a reconstituted artificial metalloenzyme containing an iridium porphyrin that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.