Article
Relationship between the LHPP Gene Polymorphism and Resting-State Brain Activity in Major Depressive Disorder.
Neural plasticity - 1 Jan 2016
Cui Lingling, Gong Xiaohong, Tang Yanqing, Kong Lingtao, Chang Miao, Geng Haiyang, Xu Ke, Wang Fei
Abstract excerpt
A single-nucleotide polymorphism at the LHPP gene (rs35936514) has been reported in genome-wide association studies to be associated with major depressive disorder (MDD). However, the neural system effects of rs35936514 that mediate the association are unknown. The present work explores whether the LHPP rs35936514 polymorphism moderates brain regional activity in MDD. A total of 160 subjects were studied: a CC...
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