Article
Glucose starvation as a selective tool for the study of adaptive mutations in Saccharomyces cerevisiae.
Journal of microbiological methods - 1 Jan 2017
Heidenreich Erich, Steinboeck Ferdinand
Abstract excerpt
Mutations not only arise in proliferating cells but also in resting - thus non-replicating - cells. Such stationary-phase mutations may occasionally enable an escape from growth repression and e.g. contribute to cancerogenesis or development of drug resistance. The most widely used condition for the study of such adaptive mutations in the eukaryotic model organism Saccharomyces cerevisiae is the starvation for a...
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