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Article

Starvation-associated mutagenesis in yeast Saccharomyces cerevisiae is affected by Ras2/cAMP signaling pathway.

Mutation research - 16 Dec 1999

Storchová Z, Vondrejs V

Abstract excerpt

The number of revertants with restored ability to form colony increases in a time-dependent manner during long-term selective starvation of dense mutant microbial cultures. This is due to starvation-associated (also called adaptive) mutations that arise in a replication independent manner. Here we report that in Saccharomyces cerevisiae the frequency of starvation-associated reversions of mutant genes whose...

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PMID: 10656486
DOI: 10.1016/s0027-5107(99)00157-8

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