Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mind your marker: the effect of common auxotrophic markers on complex traits in yeast.

The FEBS journal - 1 May 2024

Kaplan Keila, Levkovich Shon A, DeRowe Yasmin, Gazit Ehud, Laor Bar-Yosef Dana

Abstract excerpt

Yeast cells are extensively used as a key model organism owing to their highly conserved genome, metabolic pathways, and cell biology processes. To assist in genetic engineering and analysis, laboratory yeast strains typically harbor auxotrophic selection markers. When uncompensated, auxotrophic markers cause significant phenotypic bias compared to prototrophic strains and have different combinatorial influences...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetic Acid
Share to Ethanol
Share to Genetic Markers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leucine

Share to Phenotype

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to Sirolimus

Source

Identifiers

PMID: 38383986
DOI: 10.1111/febs.17095

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mind your marker: the effect of common auxotrophic markers on complex traits in yeast.PMID 38383986Read ↗

Comparative functional genomic screens of three yeast deletion collections reveal unexpected effects of genotype in response to diverse stress.Semantic proximity Read ↗

A set of genetically diverged Saccharomyces cerevisiae strains with markerless deletions of multiple auxotrophic genes.Semantic proximity Read ↗

Auxotrophic yeast strains in fundamental and applied research.Semantic proximity Read ↗

Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae.Semantic proximity Read ↗

A prototrophic deletion mutant collection for yeast metabolomics and systems biology.Semantic proximity Read ↗

A reusable method for construction of non-marker large fragment deletion yeast auxotroph strains: A practice in Torulopsis glabrata.Semantic proximity Read ↗

Global analysis of the yeast knock-out phenomeSemantic proximity Read ↗

Characterizing a panel of amino acid auxotrophs under auxotrophic starvation conditions.Semantic proximity Read ↗

Stringent mating-type-regulated auxotrophy increases the accuracy of systematic genetic interaction screens with Saccharomyces cerevisiae mutant arrays.Semantic proximity Read ↗

Loss of PDR3 alters metabolome in response to MCHM, a synthetic hydrotrope.Semantic proximity Read ↗

Evolutionary engineering and molecular characterization of a caffeine-resistant Saccharomyces cerevisiae strain.Semantic proximity Read ↗

A proteome-wide yeast degron collection for the dynamic study of protein function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.