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Article

Molecular Features of Diffuse Large B-Cell Lymphoma Associated With Primary Treatment Resistance.

Hematological oncology - 1 Jan 2025

Bock Allison M, Wenzl Kerstin, Novak Joseph P, Stokes Matthew E, Hopper Melissa A, Krull Jordan E, Dropik Abigail R, Sarangi Vivek, Ortiz Maria, Stong Nicholas, Huang C Chris, Maurer Matthew J, King Rebecca L, Farooq Umar, Wang Yucai, Witzig Thomas E, Ansell Stephen M, Habermann Thomas M, Cerhan James R, Gandhi Anita K, Nowakowski Grzegorz, Novak Anne J

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) patients that fail to achieve a complete metabolic response with frontline immunochemotherapy have a poor prognosis. Genomic profiling has led to a broader understanding of the molecular drivers in DLBCL, but it is unknown how well current classifiers identify patients that will experience primary treatment resistance (PTR). Using whole exome and RNA sequencing data from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39612356
DOI: 10.1002/hon.70006
PMCID: PMC11606593

Genes

TP53
ARID1A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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