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Article

SUMOylated MAFB promotes colorectal cancer tumorigenesis.

Oncotarget - 13 Dec 2016

Yang Lin-Sen, Zhang Xiao-Jian, Xie Yin-Yin, Sun Xiao-Jian, Zhao Ren, Huang Qiu-Hua

Abstract excerpt

The transcription factor, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B (MAFB), promotes tumorigenesis in some cancers. In this study, we found that MAFB levels were increased in clinical colorectal cancer (CRC) samples, and higher expression correlated with more advanced TNM stage. We identified MAFB amplifications in a majority of tumor types in an assessment of The Cancer Genome Atlas...

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Source

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Identifiers

PMID: 27829226
DOI: 10.18632/oncotarget.13129
PMCID: PMC5347783

Genes

MAFB
SUMO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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