Article
Unraveling molecular and clinical aspects of ALKBH5 as dual role in colorectal cancer.
The Journal of pharmacy and pharmacology - 4 Nov 2024
Memon Furqan, Nadeem Momina, Sulaiman Muhammad, Arain Mudassar Iqbal, Hani Umm-E-, Yuan Shengtao
Abstract excerpt
OBJECTIVES: This study investigates the dual role of ALKBH5, an eraser enzyme, in colorectal cancer (CRC), focusing on how N6-methyladenosine (m6A) mutations influence CRC development and progression. METHODS: We reviewed various studies that highlighted the role of ALKBH5 in colorectal cancer (CRC). This includes the impact of ALKBH5 on tumor cell behavior including immune system interactions, invasion, and...
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